Chorion Villus Sampling (CVS)

Expecting a baby brings its fair share of anticipation—and sometimes, a few concerns about health. Chorion villus sampling, or CVS, is a diagnostic test that helps answer some of those concerns early in pregnancy. It’s one of the few ways to get a definitive genetic diagnosis without waiting until the second trimester.

What is CVS, simply put?

Around the 10th to 13th week of pregnancy, a small sample of tissue—called chorionic villi—is taken from the placenta. These villi share the same genetic makeup as the fetus, so analyzing them gives a clear picture of certain chromosomal or genetic conditions. The sample is collected either through the abdomen (a thin needle guided by ultrasound) or, less often, through the cervix.

Why choose CVS?

CVS is a diagnostic test, not just a screen. That means it can confirm with high accuracy whether conditions such as Down syndrome (trisomy 21) are present—rather than indicating a chance.
Because it’s done in the first trimester, it also allows parents and healthcare providers to make well-informed decisions earlier.

Typically, it’s recommended if:

A previous screening (like NIPT or ultrasound) has flagged a higher chance of a genetic issue
There’s a family history of genetic conditions
The pregnant person is older (often 35 or above)

What to expect during the procedure

Just before the test, you’ll likely have an ultrasound to confirm how the baby is positioned and to choose the best way to access the placenta—either through the tummy (transabdominal) or cervix (transcervical).
The actual sampling takes just a few minutes, though the appointment usually spans 30–45 minutes including setup and aftercare. Mild cramping or cramping sensations are common.

How accurate is it—and what are the risks?

CVS offers very high diagnostic accuracy, often over 99%, for the conditions it tests.
However, like all invasive tests, there are small risks, including:
Miscarriage: historically estimated at around 1–2%, though some research suggests that cases may be fewer than believed
Infection or amniotic fluid leakage (rare)
Very early CVS (before 10 weeks) may slightly elevate risk of limb defects
Proper counseling and skilled providers help ensure it’s done as safely as possible.

When will you get results?

Rapid results are often available in a few days—but full comprehensive findings typically take 1–2 weeks.
If results are positive or concerning, your care provider will walk you through the options and next steps, including seeing a genetic counselor.

CVS vs. Amniocentesis: What’s different?

 

Feature
 CVS Amniocentesis
When  10–13 weeks  Around 15+ weeks
Detects Chromosomal/genetic disorders Chromosomal disorders & neural tube defects
Timeline for decisions Earlier Later
Risk  Slightly higher miscarriage risk Slightly lower miscarriage risk
CVS gives you earlier answers, whereas amniocentesis also screens for neural tube conditions.

A human touch

Deciding on CVS is personal, and good support matters. Before going ahead, you’ll meet with your care team to discuss what the test does—and doesn’t do, its benefits and risks, and what to expect. If a result shows a genetic difference, you’ll have access to compassionate counseling and medical support.

Summary overview

What it is: Diagnostic test for genetic and chromosomal disorders using placental tissue
When it’s done: Usually between 10–13 weeks of pregnancy
Why it matters: Offers definitive answers early, aiding decisions with clarity
What it involves: Sample through abdomen or cervix under ultrasound guidance
Risks: Small chance of miscarriage (about 1%), rare possible complications
Results timeline: A few days for initial, up to 2 weeks for full report

Enquire today for compassionate, professional fetal medicine support

Because every pregnancy deserves specialised attention and compassion